About Event

Welcome to the 3rd Annual Blood-Brain Barrier Summit

Enhancing Drug Delivery Across the Blood-Brain Barrier to Develop More Clinically Meaningful Therapeutics for Neurodegenerative Diseases

Delivering therapeutics across the blood-brain barrier (BBB) has been a major obstacle to successful drug development in neurodegeneration. Delivery across this extremely complex interface requires serious collaboration.

Join BBB specialists, from the likes of AbbVie, Merck, Ossianix, Novartis and Roche, online to scrutinize the progress of existing approaches to delivering more of your biologic therapeutic across the BBB to develop a clinically defining neurodegenerative treatment.

The digital Blood-Brain Barrier Summit is a unique opportunity to:

Explore the translation of BBB-penetrating antibodies to non-human primates, and new possibilities for in vivo brain imaging of antibody neuropharamacokinetics with Ossianix, ABL Bio and Uppsala University
.
Uncover advances in CNS gene therapy, new generation vectors for intravenous delivery, and the challenges of scaling up for CNS delivery beyond highly specialized centers with AskBio
.
Discover the role of neural extracellular vesicles in non-invasive CNS drug delivery, and how the properties of extracellular vesicles can be enhanced with unique surface modifications with Aruna Bio
.
Hear how focused ultrasound has been used to target the striatum in patients with Parkinson’s Disease, and learn the main obstacles to these techniques as well as what’s next on the horizon with José Obeso
.
Hear the challenges and opportunities in nanoparticle engineering for brain targeting, and discuss the fast delivery of nucleic acid medicines (siRNA, mRNA) and peptide cargoes to the brain parenchyma on intravenous injection with Lauren Science, INSERM and Newcastle University
.
Uncover current controversies and progress in human induced pluripotent stem cell derived brain endothelial cells and various approaches to driving innovation in models of the BBB with AbbVie, Raphael Lis, National Research Council of Canada and Johns Hopkins Institute for NanoBioTechnology
.

Access High-quality Content and Networking Opportunities Live and Direct From Your Home or Office

  • Tune into live presentations from our expert speakers
  • Engage with your peers in a facilitated speed networking session
  • Establish connections with speakers and attendees through private and public chatrooms, including video calling for 121 private conversations
  • Save each session to your personal calendar to ensure you don’t miss a particular presentation
  • Set up a personalized profile and engage with speakers and attendees with similar interests or particular areas of expertise